Under the Radar Screen: How Bugs Trick Our Immune Defenses, MIT OpenCourseWare (OCW)

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Massachusetts Institute of Technology,
77 Massachusetts Avenue,
Cambridge, MA 02139-4307,

Course Description,
In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples.