The X in Sex: A Genetic, Medical, and Evolutionary View of the X Chromosome, MIT OpenCourseWare (OCW)

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Massachusetts Institute of Technology,
77 Massachusetts Avenue,
Cambridge, MA 02139-4307,

Course Description,
This course will explore a diverse collection of striking biological phenomena associated with the X chromosome. We will examine the genetic basis and significance of several X-linked mutations. We will also discuss why men are more likely than women to display X-linked traits. We will look at the different mechanisms by which X chromosome gene expression is equalized in mammals, flies, and worms and how these mechanisms can yield unusual phenotypes. Throughout our discussions of the X chromosome we will use both recent and classic primary research papers to learn about this chromosome's fascinating biology.